Motif ID: NFY{A,B,C}.p2

Z-value: 2.545


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_412045090.393.5e-02Click!
NFYAchr6_+_410406870.346.6e-02Click!
NFYBchr12_-_1045318750.319.1e-02Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_54863672 9.016 NM_001130851
NM_005192
CDKN3

cyclin-dependent kinase inhibitor 3

chr17_-_38574042 7.350 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr17_+_6347733 7.264 NM_001195228
NM_019013
FAM64A

family with sequence similarity 64, member A

chr19_-_14247400 7.245 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr2_+_10262853 7.241 NM_001034
RRM2
ribonucleotide reductase M2
chr2_+_27008912 6.857 CENPA
centromere protein A
chr17_+_57232859 6.619 NM_018304
PRR11
proline rich 11
chr19_+_4910339 6.354 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr6_+_80714389 6.333 TTK
TTK protein kinase
chr2_+_10262694 6.191 NM_001165931
RRM2
ribonucleotide reductase M2
chr6_+_80714321 6.125 NM_001166691
NM_003318
TTK

TTK protein kinase

chr17_-_76183074 5.968 NM_003258
TK1
thymidine kinase 1, soluble
chr15_-_41624760 5.808 NM_007280
OIP5
Opa interacting protein 5
chr19_-_14247267 5.784 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr5_+_162887516 5.607 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr20_+_30326903 5.499 NM_012112
TPX2
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr5_+_68462948 5.469 CCNB1
cyclin B1
chr17_+_26646120 5.405 NM_014573
TMEM97
transmembrane protein 97
chr15_+_41625052 5.192 NUSAP1
nucleolar and spindle associated protein 1
chr15_+_41624891 5.191 NM_001243142
NM_001243143
NM_001243144
NM_016359
NM_018454
NUSAP1




nucleolar and spindle associated protein 1




chr15_+_41625152 5.130 NUSAP1
nucleolar and spindle associated protein 1
chr10_+_62538250 4.903 CDK1
cyclin-dependent kinase 1
chr2_+_27008881 4.892 NM_001809
NM_001042426
CENPA

centromere protein A

chr10_+_62538088 4.840 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr14_-_55658205 4.779 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr2_-_234763145 4.682 HJURP
Holliday junction recognition protein
chr2_-_234763182 4.670 NM_018410
HJURP
Holliday junction recognition protein
chr19_-_14228560 4.630 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr5_-_64858931 4.565 NM_022145
CENPK
centromere protein K
chr5_+_68462985 4.426 CCNB1
cyclin B1
chr1_-_197115566 4.249 NM_001206846
NM_018136
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr11_-_118966175 4.078 NM_002105
H2AFX
H2A histone family, member X
chr17_-_8113862 3.980 NM_004217
AURKB
aurora kinase B
chr8_+_25316512 3.925 NM_152562
CDCA2
cell division cycle associated 2
chr20_-_54967221 3.894 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr1_+_43824598 3.894 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr6_-_136571404 3.868 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr9_+_91926109 3.854 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr2_-_111435604 3.804 NM_004336
BUB1
budding uninhibited by benzimidazoles 1 homolog (yeast)
chr1_+_214776494 3.725 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr11_-_118966103 3.721 H2AFX
H2A histone family, member X
chr4_-_174255454 3.665 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr15_+_59397276 3.602 NM_004701
CCNB2
cyclin B2
chr6_+_31126340 3.600 TCF19
transcription factor 19
chr1_+_214776582 3.503 CENPF
centromere protein F, 350/400kDa (mitosin)
chr6_+_31126114 3.418 NM_001077511
NM_007109
TCF19

transcription factor 19

chr16_+_2479417 3.379 CCNF
cyclin F
chr16_+_2479387 3.347 NM_001761
CCNF
cyclin F
chr11_-_71159442 3.333 NM_001163817
NM_001360
DHCR7

7-dehydrocholesterol reductase

chr11_-_71159371 3.307 DHCR7
7-dehydrocholesterol reductase
chr10_+_102107256 3.198


chr1_-_211848820 3.173 NM_001204182
NM_001204183
NM_002497
NEK2


NIMA (never in mitosis gene a)-related kinase 2


chr19_-_55919324 3.113 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr5_+_68462836 3.104 NM_031966
CCNB1
cyclin B1
chr12_-_120315074 3.097 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr3_-_120461350 3.063


chr6_+_160183510 3.032 ACAT2
acetyl-CoA acetyltransferase 2
chr17_+_46970128 2.944 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr12_-_6961044 2.860 CDCA3
cell division cycle associated 3
chr19_-_55918980 2.858 UBE2S
ubiquitin-conjugating enzyme E2S
chr15_-_64673569 2.789 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr12_-_123717645 2.759 MPHOSPH9
M-phase phosphoprotein 9
chr22_+_19467413 2.699 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr12_-_2986299 2.693 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chr10_+_94352809 2.689 NM_004523
KIF11
kinesin family member 11
chr22_+_19467467 2.676 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr1_-_68962679 2.670 DEPDC1
DEP domain containing 1
chr10_+_102106958 2.659 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr17_+_38444130 2.653 CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr12_-_2986095 2.652 FOXM1
forkhead box M1
chr20_+_25388328 2.644 GINS1
GINS complex subunit 1 (Psf1 homolog)
chr10_+_94352873 2.622 KIF11
kinesin family member 11
chr11_+_13690246 2.621 FAR1
fatty acyl CoA reductase 1
chr6_+_24775154 2.608 NM_001251989
NM_001251990
NM_015895
GMNN


geminin, DNA replication inhibitor


chr11_-_61584451 2.606 NM_013402
FADS1
fatty acid desaturase 1
chr2_-_136288768 2.581 NM_032143
ZRANB3
zinc finger, RAN-binding domain containing 3
chr12_+_49716970 2.580 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr8_+_126010719 2.578 NM_003129
SQLE
squalene epoxidase
chr11_-_61584228 2.569 FADS1
fatty acid desaturase 1
chr6_+_160183062 2.568 ACAT2
acetyl-CoA acetyltransferase 2
chrX_+_69509878 2.562 NM_012310
KIF4A
kinesin family member 4A
chr6_+_160182988 2.537 NM_005891
ACAT2
acetyl-CoA acetyltransferase 2
chr20_+_25388320 2.496 NM_021067
GINS1
GINS complex subunit 1 (Psf1 homolog)
chr4_+_1723233 2.486 TACC3
transforming, acidic coiled-coil containing protein 3
chr19_+_4909447 2.481 NM_001048201
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr9_-_139965012 2.470 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr20_+_47662782 2.461 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr4_+_1723212 2.449 NM_006342
TACC3
transforming, acidic coiled-coil containing protein 3
chr12_+_110011616 2.428 MVK
mevalonate kinase
chr16_-_84651639 2.426 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr1_-_68962726 2.422 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr16_-_84651519 2.420 COTL1
coactosin-like 1 (Dictyostelium)
chr10_+_102107074 2.414 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr1_-_200589856 2.405 NM_014875
KIF14
kinesin family member 14
chr16_+_23690190 2.404 PLK1
polo-like kinase 1
chr11_+_13690151 2.376 NM_032228
FAR1
fatty acyl CoA reductase 1
chr3_+_172468469 2.376 ECT2
epithelial cell transforming sequence 2 oncogene
chr16_+_23690234 2.368 PLK1
polo-like kinase 1
chr3_-_185826748 2.342 NM_004454
ETV5
ets variant 5
chr11_-_134093869 2.331 NCAPD3
non-SMC condensin II complex, subunit D3
chr11_+_13690263 2.330 FAR1
fatty acyl CoA reductase 1
chr12_+_110011499 2.329 NM_000431
NM_001114185
MVK

mevalonate kinase

chr10_+_94352960 2.310 KIF11
kinesin family member 11
chr10_+_95256348 2.297 NM_001127182
NM_018131
CEP55

centrosomal protein 55kDa

chr1_+_120839004 2.290 NM_001100910
FAM72B
family with sequence similarity 72, member B
chr4_+_166248816 2.278 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr17_+_38444134 2.270 NM_001254
CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr17_+_38444151 2.245 CDC6
cell division cycle 6 homolog (S. cerevisiae)
chr16_+_23690160 2.241 PLK1
polo-like kinase 1
chr7_+_129710572 2.229 KLHDC10
kelch domain containing 10
chr8_+_11660272 2.219 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr5_-_59995938 2.214 NM_001145208
NM_018369
DEPDC1B

DEP domain containing 1B

chr1_-_47779651 2.198 NM_001048166
NM_003035
STIL

SCL/TAL1 interrupting locus

chr5_+_137514753 2.196 KIF20A
kinesin family member 20A
chr5_+_74632992 2.184 NM_000859
NM_001130996
HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

chr5_+_154393259 2.181 NM_001099293
KIF4B
kinesin family member 4B
chr11_+_61891414 2.165 NM_001040694
NM_020238
INCENP

inner centromere protein antigens 135/155kDa

chr1_+_155278538 2.151 NM_001135822
NM_001242824
NM_001242825
NM_002004
FDPS



farnesyl diphosphate synthase



chr2_+_201390848 2.146 NM_001160033
NM_001160046
NM_152524
SGOL2


shugoshin-like 2 (S. pombe)


chr14_+_24641204 2.143 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr1_-_143913118 2.130 NM_207418
FAM72D
family with sequence similarity 72, member D
chr16_+_23690191 2.118 NM_005030
PLK1
polo-like kinase 1
chrX_+_17755562 2.091 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr16_+_23690212 2.090 PLK1
polo-like kinase 1
chr1_+_155278727 2.053 FDPS
farnesyl diphosphate synthase
chr15_+_90118740 2.043 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr5_+_74633043 2.036 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr8_+_11660207 2.032 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_-_19262424 2.019 NM_024680
E2F8
E2F transcription factor 8
chr1_+_212209129 2.014 DTL
denticleless homolog (Drosophila)
chrX_+_48555124 2.005 NM_003173
SUV39H1
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr8_+_11660520 1.995 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr2_-_113522167 1.990 NM_152515
CKAP2L
cytoskeleton associated protein 2-like
chr9_-_99180661 1.961 NM_153695
ZNF367
zinc finger protein 367
chr1_+_155278677 1.958 NM_001135821
FDPS
farnesyl diphosphate synthase
chr17_-_57232799 1.952 NM_001100595
NM_182620
SKA2

spindle and kinetochore associated complex subunit 2

chr20_+_44441671 1.941 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr20_+_44441334 1.925 UBE2C
ubiquitin-conjugating enzyme E2C
chr8_+_26435339 1.918 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr16_+_46723577 1.917 ORC6
PPA2
origin recognition complex, subunit 6
pyrophosphatase (inorganic) 2
chr10_+_102107001 1.910 SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr20_+_44441247 1.902 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr12_-_6960406 1.899 NM_031299
CDCA3
cell division cycle associated 3
chr2_+_97001506 1.899 NCAPH
non-SMC condensin I complex, subunit H
chr17_+_57233100 1.894 PRR11
proline rich 11
chr8_+_11660179 1.891 NM_004462
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr11_+_13690230 1.862 FAR1
fatty acyl CoA reductase 1
chr20_+_37554954 1.858 NM_030919
FAM83D
family with sequence similarity 83, member D
chr20_+_37555055 1.834 FAM83D
family with sequence similarity 83, member D
chr15_+_69706619 1.827 NM_004856
NM_138555
KIF23

kinesin family member 23

chr8_+_48873446 1.822 MCM4
minichromosome maintenance complex component 4
chr8_+_26435466 1.817 DPYSL2
dihydropyrimidinase-like 2
chr4_+_75310852 1.802 NM_001657
AREG
amphiregulin
chr1_-_202311048 1.795 UBE2T
ubiquitin-conjugating enzyme E2T (putative)
chr8_+_6565870 1.795 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr2_+_61292999 1.793 NM_001129993
KIAA1841
KIAA1841
chr19_-_14228362 1.783 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr2_+_97001463 1.778 NM_015341
NCAPH
non-SMC condensin I complex, subunit H
chr1_+_154947147 1.767 CKS1B
CDC28 protein kinase regulatory subunit 1B
chr14_+_24641084 1.766 REC8
REC8 homolog (yeast)
chr4_-_185655215 1.761 NM_024629
MLF1IP
MLF1 interacting protein
chr1_-_202311066 1.757 NM_014176
UBE2T
ubiquitin-conjugating enzyme E2T (putative)
chr2_+_191745912 1.754 GLS
glutaminase
chr1_+_154947166 1.734 CKS1B
CDC28 protein kinase regulatory subunit 1B
chr11_+_13299329 1.732 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr2_-_61765394 1.731 NM_003400
XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_+_61293038 1.725 KIAA1841
KIAA1841
chr1_+_45205533 1.723 KIF2C
kinesin family member 2C
chrX_-_100662905 1.722 NM_000169
GLA
galactosidase, alpha
chr10_+_102106771 1.721 NM_005063
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr4_+_1873035 1.720 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr4_+_75230856 1.717 NM_001432
EREG
epiregulin
chr17_+_70117154 1.714 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr22_+_29999605 1.714 NF2
neurofibromin 2 (merlin)
chr7_+_155089614 1.710 INSIG1
insulin induced gene 1
chr1_+_45205466 1.689 NM_006845
KIF2C
kinesin family member 2C
chr12_-_89746238 1.686 DUSP6
dual specificity phosphatase 6
chr11_-_66725790 1.677 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr3_+_37034983 1.657 MLH1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr8_+_11660297 1.646 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chrX_-_71458760 1.642 NM_017669
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr11_-_94964209 1.640 NM_144665
SESN3
sestrin 3
chr21_-_47648685 1.632 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr10_-_1094854 1.628 IDI1
isopentenyl-diphosphate delta isomerase 1
chr19_-_11266451 1.622 NM_182513
SPC24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_+_154947116 1.621 NM_001826
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr8_+_27631902 1.613 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr2_-_128784864 1.603 NM_001145928
NM_024545
SAP130

Sin3A-associated protein, 130kDa

chr8_-_95487284 1.593 NM_001205262
NM_012415
RAD54B

RAD54 homolog B (S. cerevisiae)

chrX_-_100662788 1.591 GLA
galactosidase, alpha
chr12_-_50419160 1.574 NM_001126103
NM_001126104
NM_013277
RACGAP1


Rac GTPase activating protein 1


chr11_+_13299349 1.569 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr8_-_25315941 1.566 NM_017634
KCTD9
potassium channel tetramerisation domain containing 9
chr5_-_172755195 1.564 STC2
stanniocalcin 2
chr1_+_212208918 1.562 NM_016448
DTL
denticleless homolog (Drosophila)
chr10_-_58121011 1.556 ZWINT
ZW10 interactor
chr10_-_58121019 1.554 NM_001005413
NM_007057
NM_032997
ZWINT


ZW10 interactor


chr1_+_38158176 1.547 CDCA8
cell division cycle associated 8
chr1_+_38158189 1.547 CDCA8
cell division cycle associated 8
chr1_+_212209112 1.538 DTL
denticleless homolog (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.77 4.86e-42 GO:0007049 cell cycle
2.93 4.54e-38 GO:0022402 cell cycle process
3.12 1.02e-37 GO:0022403 cell cycle phase
3.23 2.45e-34 GO:0000278 mitotic cell cycle
3.56 1.08e-32 GO:0000279 M phase
3.90 6.17e-28 GO:0000087 M phase of mitotic cell cycle
3.75 1.47e-24 GO:0000280 nuclear division
3.75 1.47e-24 GO:0007067 mitosis
3.63 1.89e-23 GO:0048285 organelle fission
3.25 2.79e-20 GO:0010564 regulation of cell cycle process
2.53 2.28e-18 GO:0051726 regulation of cell cycle
1.34 5.25e-17 GO:0044237 cellular metabolic process
1.18 1.03e-16 GO:0009987 cellular process
1.43 3.44e-16 GO:0044260 cellular macromolecule metabolic process
1.82 5.38e-16 GO:0006996 organelle organization
3.52 9.34e-16 GO:0071156 regulation of cell cycle arrest
1.53 1.23e-15 GO:0034641 cellular nitrogen compound metabolic process
1.57 5.14e-15 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51 9.89e-15 GO:0006807 nitrogen compound metabolic process
3.48 1.24e-14 GO:0000075 cell cycle checkpoint
2.87 1.57e-14 GO:0051301 cell division
1.31 1.83e-14 GO:0044238 primary metabolic process
1.64 1.94e-14 GO:0090304 nucleic acid metabolic process
1.59 4.36e-14 GO:0009058 biosynthetic process
2.99 5.06e-14 GO:0051325 interphase
2.96 2.67e-13 GO:0051329 interphase of mitotic cell cycle
1.27 2.95e-13 GO:0008152 metabolic process
1.56 3.82e-12 GO:0044249 cellular biosynthetic process
4.79 1.02e-11 GO:0000236 mitotic prometaphase
1.33 3.45e-11 GO:0043170 macromolecule metabolic process
4.21 6.58e-11 GO:0007059 chromosome segregation
1.50 1.25e-10 GO:0071842 cellular component organization at cellular level
1.48 2.76e-10 GO:0071841 cellular component organization or biogenesis at cellular level
2.18 3.46e-10 GO:0006259 DNA metabolic process
1.92 3.93e-09 GO:0033554 cellular response to stress
6.34 4.50e-09 GO:0016126 sterol biosynthetic process
2.07 1.02e-08 GO:0051276 chromosome organization
3.10 1.09e-08 GO:0006260 DNA replication
6.78 1.30e-08 GO:0006695 cholesterol biosynthetic process
1.39 2.60e-08 GO:0016043 cellular component organization
1.37 4.75e-08 GO:0071840 cellular component organization or biogenesis
1.57 9.80e-08 GO:0009059 macromolecule biosynthetic process
1.57 1.07e-07 GO:0034645 cellular macromolecule biosynthetic process
3.30 1.19e-07 GO:0006310 DNA recombination
3.17 1.32e-07 GO:0071103 DNA conformation change
2.56 3.49e-07 GO:0007017 microtubule-based process
3.23 1.44e-06 GO:0006323 DNA packaging
2.00 6.90e-06 GO:0006974 response to DNA damage stimulus
4.93 1.08e-05 GO:0000819 sister chromatid segregation
3.30 1.54e-05 GO:0065004 protein-DNA complex assembly
2.38 1.65e-05 GO:0007346 regulation of mitotic cell cycle
2.95 1.83e-05 GO:0000082 G1/S transition of mitotic cell cycle
2.23 2.30e-05 GO:0033043 regulation of organelle organization
2.20 2.34e-05 GO:0006281 DNA repair
3.21 3.08e-05 GO:0007126 meiosis
3.21 3.08e-05 GO:0051327 M phase of meiotic cell cycle
2.15 3.30e-05 GO:0034622 cellular macromolecular complex assembly
3.18 3.85e-05 GO:0051321 meiotic cell cycle
3.12 5.98e-05 GO:0071824 protein-DNA complex subunit organization
3.15 8.12e-05 GO:0000086 G2/M transition of mitotic cell cycle
3.01 8.21e-05 GO:0010639 negative regulation of organelle organization
1.46 9.89e-05 GO:0016070 RNA metabolic process
1.77 1.07e-04 GO:0065003 macromolecular complex assembly
3.55 1.25e-04 GO:0000216 M/G1 transition of mitotic cell cycle
4.70 1.76e-04 GO:0000070 mitotic sister chromatid segregation
1.29 1.84e-04 GO:0031323 regulation of cellular metabolic process
2.79 1.97e-04 GO:0051052 regulation of DNA metabolic process
5.59 2.60e-04 GO:0006271 DNA strand elongation involved in DNA replication
1.39 3.65e-04 GO:0048523 negative regulation of cellular process
4.18 5.17e-04 GO:0007051 spindle organization
1.41 6.36e-04 GO:0010467 gene expression
5.22 7.09e-04 GO:0022616 DNA strand elongation
3.14 8.26e-04 GO:0006334 nucleosome assembly
3.27 1.20e-03 GO:0007088 regulation of mitosis
3.27 1.20e-03 GO:0051783 regulation of nuclear division
2.28 1.33e-03 GO:0051129 negative regulation of cellular component organization
1.16 1.60e-03 GO:0050794 regulation of cellular process
1.62 1.64e-03 GO:0043933 macromolecular complex subunit organization
1.40 1.74e-03 GO:0044281 small molecule metabolic process
1.33 1.76e-03 GO:0044267 cellular protein metabolic process
2.85 2.18e-03 GO:0051320 S phase
2.72 2.25e-03 GO:0007093 mitotic cell cycle checkpoint
1.82 2.31e-03 GO:0034621 cellular macromolecular complex subunit organization
2.98 2.36e-03 GO:0031497 chromatin assembly
2.28 2.39e-03 GO:0045786 negative regulation of cell cycle
2.33 2.53e-03 GO:0006457 protein folding
1.24 2.64e-03 GO:0019222 regulation of metabolic process
2.54 2.90e-03 GO:0000226 microtubule cytoskeleton organization
1.53 2.91e-03 GO:0022607 cellular component assembly
1.61 3.56e-03 GO:0051128 regulation of cellular component organization
1.50 3.87e-03 GO:0044085 cellular component biogenesis
3.16 4.01e-03 GO:0006275 regulation of DNA replication
2.89 4.26e-03 GO:0016125 sterol metabolic process
2.59 4.30e-03 GO:0006333 chromatin assembly or disassembly
1.26 4.63e-03 GO:0060255 regulation of macromolecule metabolic process
1.33 5.30e-03 GO:0048519 negative regulation of biological process
2.83 6.22e-03 GO:0034728 nucleosome organization
8.43 6.91e-03 GO:0000085 G2 phase of mitotic cell cycle
8.43 6.91e-03 GO:0051319 G2 phase
3.71 7.36e-03 GO:0070507 regulation of microtubule cytoskeleton organization
1.25 8.06e-03 GO:0080090 regulation of primary metabolic process
1.75 8.06e-03 GO:0044265 cellular macromolecule catabolic process
2.43 8.20e-03 GO:0010498 proteasomal protein catabolic process
2.43 8.20e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.47 9.93e-03 GO:0032886 regulation of microtubule-based process
2.83 1.05e-02 GO:0006694 steroid biosynthetic process
1.14 1.16e-02 GO:0050789 regulation of biological process
1.60 1.26e-02 GO:0071844 cellular component assembly at cellular level
2.67 1.27e-02 GO:0031570 DNA integrity checkpoint
2.67 1.27e-02 GO:0051640 organelle localization
1.51 1.27e-02 GO:0032268 regulation of cellular protein metabolic process
4.52 1.29e-02 GO:0000724 double-strand break repair via homologous recombination
4.52 1.29e-02 GO:0000725 recombinational repair
1.61 1.34e-02 GO:0012501 programmed cell death
2.85 1.48e-02 GO:0008203 cholesterol metabolic process
1.47 1.60e-02 GO:0044248 cellular catabolic process
2.68 1.80e-02 GO:0000084 S phase of mitotic cell cycle
1.60 2.31e-02 GO:0006915 apoptosis
4.25 2.69e-02 GO:0031110 regulation of microtubule polymerization or depolymerization
3.10 3.03e-02 GO:0006261 DNA-dependent DNA replication
1.73 3.16e-02 GO:0007010 cytoskeleton organization
1.70 4.76e-02 GO:0051338 regulation of transferase activity
1.54 4.91e-02 GO:0031399 regulation of protein modification process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.27 1.18e-46 GO:0044424 intracellular part
1.25 2.55e-45 GO:0005622 intracellular
1.32 7.65e-41 GO:0043229 intracellular organelle
1.31 2.10e-40 GO:0043226 organelle
1.34 5.83e-38 GO:0043227 membrane-bounded organelle
1.34 7.21e-38 GO:0043231 intracellular membrane-bounded organelle
1.47 1.14e-30 GO:0044422 organelle part
1.48 1.26e-30 GO:0044446 intracellular organelle part
1.47 3.71e-30 GO:0005634 nucleus
1.31 9.65e-27 GO:0005737 cytoplasm
1.83 1.33e-26 GO:0070013 intracellular organelle lumen
1.81 3.87e-26 GO:0031974 membrane-enclosed lumen
1.80 2.34e-25 GO:0043233 organelle lumen
1.77 1.30e-21 GO:0044428 nuclear part
1.79 7.08e-19 GO:0031981 nuclear lumen
2.55 4.63e-18 GO:0005694 chromosome
1.34 4.31e-17 GO:0044444 cytoplasmic part
4.25 1.52e-16 GO:0000793 condensed chromosome
1.86 2.24e-15 GO:0005654 nucleoplasm
1.46 1.32e-14 GO:0032991 macromolecular complex
1.54 1.91e-14 GO:0043228 non-membrane-bounded organelle
1.54 1.91e-14 GO:0043232 intracellular non-membrane-bounded organelle
2.52 2.28e-14 GO:0044427 chromosomal part
1.62 1.26e-13 GO:0005829 cytosol
3.43 7.61e-13 GO:0005819 spindle
2.14 1.90e-12 GO:0015630 microtubule cytoskeleton
1.47 6.75e-12 GO:0043234 protein complex
3.65 1.19e-11 GO:0000775 chromosome, centromeric region
4.38 2.76e-09 GO:0000779 condensed chromosome, centromeric region
4.11 3.31e-09 GO:0000776 kinetochore
2.81 9.56e-09 GO:0000228 nuclear chromosome
4.35 1.88e-08 GO:0000777 condensed chromosome kinetochore
4.82 5.79e-08 GO:0000794 condensed nuclear chromosome
4.38 8.88e-08 GO:0000922 spindle pole
2.91 1.41e-07 GO:0044454 nuclear chromosome part
1.88 2.70e-07 GO:0044429 mitochondrial part
1.54 6.01e-06 GO:0005739 mitochondrion
1.77 7.63e-06 GO:0031967 organelle envelope
1.74 1.87e-05 GO:0031975 envelope
2.37 3.86e-05 GO:0005813 centrosome
1.46 6.53e-05 GO:0005856 cytoskeleton
2.16 7.34e-05 GO:0005874 microtubule
2.17 2.65e-04 GO:0005759 mitochondrial matrix
1.05 3.39e-04 GO:0044464 cell part
1.05 3.50e-04 GO:0005623 cell
1.97 6.15e-04 GO:0005815 microtubule organizing center
1.51 7.74e-04 GO:0044430 cytoskeletal part
7.67 2.97e-03 GO:0000780 condensed nuclear chromosome, centromeric region
3.19 3.28e-03 GO:0034399 nuclear periphery
1.58 4.20e-03 GO:0044451 nucleoplasm part
3.27 7.52e-03 GO:0030496 midbody
1.70 1.19e-02 GO:0005740 mitochondrial envelope
3.11 1.48e-02 GO:0016363 nuclear matrix
1.99 1.48e-02 GO:0000785 chromatin
3.53 3.77e-02 GO:0008287 protein serine/threonine phosphatase complex
2.54 3.91e-02 GO:0032993 protein-DNA complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.26 3.49e-14 GO:0005515 protein binding
1.12 1.13e-09 GO:0005488 binding
1.43 4.55e-07 GO:0000166 nucleotide binding
1.51 3.02e-06 GO:0030554 adenyl nucleotide binding
1.51 5.05e-06 GO:0005524 ATP binding
1.50 5.64e-06 GO:0032559 adenyl ribonucleotide binding
1.22 1.97e-05 GO:0003824 catalytic activity
1.42 3.03e-05 GO:0017076 purine nucleotide binding
1.43 3.33e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.42 4.84e-05 GO:0032553 ribonucleotide binding
1.42 4.84e-05 GO:0032555 purine ribonucleotide binding
4.22 1.46e-03 GO:0003678 DNA helicase activity
1.59 1.52e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
4.82 1.53e-03 GO:0004003 ATP-dependent DNA helicase activity
3.59 1.55e-03 GO:0003697 single-stranded DNA binding
1.60 2.09e-03 GO:0017111 nucleoside-triphosphatase activity
1.58 2.25e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.57 3.30e-03 GO:0016462 pyrophosphatase activity
1.25 4.20e-03 GO:0003676 nucleic acid binding
3.25 6.96e-03 GO:0008094 DNA-dependent ATPase activity
2.26 9.47e-03 GO:0000287 magnesium ion binding
10.04 1.55e-02 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
2.15 1.55e-02 GO:0043566 structure-specific DNA binding